Description
MOTS-c is a 16-amino-acid mitochondrial-derived peptide (MDP) encoded within the mitochondrial 12S rRNA gene region. Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg-OH. Molecular formula: C101H152N28O22S2; molecular weight: 2174.6 g/mol; CAS 1627580-64-6.
Research on MOTS-c has examined its translocation to the nucleus under metabolic stress, activation of AMP-activated protein kinase (AMPK), and regulation of nuclear gene expression involved in glucose and lipid metabolism in cell culture and animal models.
Supplied as a lyophilized powder for reconstitution, each batch is analyzed by HPLC to confirm purity and identity.
For laboratory research use only. Not for human or veterinary use, and not intended for diagnostic or therapeutic application.
