Description
SNAP-8 (Acetyl Octapeptide-3) is a synthetic octapeptide structurally derived from the N-terminal region of SNAP-25, a core component of the SNARE complex responsible for vesicle docking and neurotransmitter exocytosis at nerve terminals. Sequence: Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2. Molecular formula: C42H72N16O15S; molecular weight: 1073.2 g/mol.
In vitro and ex vivo research has examined SNAP-8’s ability to interfere competitively with SNARE complex assembly, modulating acetylcholine release at the neuromuscular junction without proteolytic activity. Comparative studies have evaluated its performance alongside related hexapeptide and heptapeptide SNARE-interfering sequences in dermal fibroblast and skin explant models.
This product is supplied as a lyophilized powder intended for laboratory and cosmetic-ingredient research applications. Purity is confirmed by third-party HPLC analysis for each production batch.
For research use only. Not for human or veterinary use, and not intended for topical, oral, or injectable application outside a controlled laboratory setting.
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